Faculty of Agriculture: Departments/Courses under faculty of Agriculture include Agricultural Economics and Extension, Crop Science, Soil Science, Animal Science, Home Economics, Fisheries & Aquaculture, Food Science & Technology & Forestry & Wildlife.
Faculty of Arts: Departments/Courses under faculty of Arts include Communication Arts, English, Foreign Languages, History & International Studies, Linguistics & Nigerian Languages, Philosophy, Religious & Cultural Studies, Music & Theatre Arts.
Faculty of Basic Medical Science: Departments/Courses under faculty of basic medical science in Uniuyo include Anatomy, Physiology & Biochemistry.
Faculty of Business Administration: Departments under Faculty of Business Administration include Accounting, Banking & Finance, Insurance, Business Management & Marketing.
Faculty of Clinical Sciences: Department of Medicine.
Faculty of Education: Departments under Faculty of Education include: Efik/Ibibio, French, History, Fine Arts, Music, Religious Studies, Social Studies, Special Education, Economics, Geography, Guidance & Counselling, Political Science, Health Education, Physical Education, Agriculture, Home Economics, Business Education,(Accounting), Business Education(Office Management), Technical Education, Computer Education, Biology, Chemistry, Integrated Science, Mathematics, Physics, Pre-Primary Education & Library Science.
Faculty of Engineering: Agriculture & Food Engineering, Chemical & Petroleum Engineering, Civil Engineering, Electrical/Electronics Engineering, Computer Engineering & Mechanical Engineering.
Faculty of Environmental Studies: Departments include Architecture, Building, Estate Management, Geoinformatics & Surveying, Quantity Surveying, Urban & Regional Planning & Fine & Industrial Arts.
Faculty of Law: Department of Law.
Faculty of Pharmacy: Department of Pharmacy
Faculty of Science: Botany & Ecological Studies, Chemistry, Microbiology, Statistics, Computer Science, Zoology & Physics.
Faculty of Social Science: Economics, Geography & Regional Planning, Political Science & Public Administration, Sociology & Anthropology & Psychology.